Adverse Events With Ketamine Versus Ketofol for Procedural Sedation on Adults: A Double-blind, Randomized Controlled Trial
نویسندگان
چکیده
منابع مشابه
Ketamine-propofol combination (ketofol) versus propofol alone for emergency department procedural sedation and analgesia: a randomized double-blind trial.
STUDY OBJECTIVE We determine whether a 1:1 mixture of ketamine and propofol (ketofol) for emergency department (ED) procedural sedation results in a 13% or more absolute reduction in adverse respiratory events compared with propofol alone. METHODS Participants were randomized to receive either ketofol or propofol in a double-blind fashion. Inclusion criteria were aged 14 years or older and Am...
متن کاملAdverse events associated with ketamine for procedural sedation in adults.
STUDY OBJECTIVES Ketamine is widely used as a procedural sedation agent in pediatrics, where its safety and efficacy are supported by numerous studies. Emergency physicians use ketamine infrequently in adults, as it is believed to have a more significant side effect profile in this population. However, adult data on ketamine use in the emergency medicine literature are sparse. Our objective was...
متن کاملEffect of Ondansetron on the Incidence of Ketamine Associated Vomiting in Procedural Sedation and Analgesia in Children: A Double-Blind, Randomized, Placebo-Controlled Trial
Background Vomiting is a common side effect of ketamine in children's sedation and there is still controversy about the use of an anti-emetic drug along with ketamine to reduce this complication. The aim of this study was to evaluate the effectiveness of ondansetron in controlling vomiting induced by intramuscular (IM), and intravenous (IV) ketamine for procedural sedation and analgesia in chil...
متن کاملPropofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
STUDY OBJECTIVE We determine whether emergency physician-provided deep sedation with 1:1 ketofol versus propofol results in fewer adverse respiratory events requiring physician intervention when used for procedural sedation and analgesia. METHODS Consenting patients requiring deep sedation were randomized to receive either ketofol or propofol in a double-blind fashion according to a weight-ba...
متن کاملA blinded, randomized controlled trial to evaluate ketamine/propofol versus ketamine alone for procedural sedation in children.
STUDY OBJECTIVE The primary objective is to compare total sedation time when ketamine/propofol is used compared with ketamine alone for pediatric procedural sedation and analgesia. Secondary objectives include time to recovery, adverse events, efficacy, and satisfaction scores. METHODS Children (aged 2 to 17 years) requiring procedural sedation and analgesia for management of an isolated orth...
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ژورنال
عنوان ژورنال: Academic Emergency Medicine
سال: 2017
ISSN: 1069-6563
DOI: 10.1111/acem.13226